- Claude Bernard -

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

Oct 2020 FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy. https://www.medrxiv.org/content/10.1101/2020.10.06.20208116v1 

Aug 2020 Mechanisms of Key Innate Immune Cells in Early- and Late-Onset Preeclampsia. Frontiers in Immunology.

https://www.frontiersin.org/articles/10.3389/fimmu.2020.01864/full

July 2020 Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment. Journal of Clinical Endocrinology and Metabolism. https://doi.org/10.1210/clinem/dgaa403

July 2020 Cardiac Health in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia. Journal of Paediatrics and Child Health. https://onlinelibrary.wiley.com/doi/10.1111/jpc.14868

June 2020 Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives. Cells. https://www.mdpi.com/2073-4409/9/6/1503

 

May 2020 Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections. Front. Bioeng. Biotechnol. https://doi.org/10.3389/fbioe.2020.00554 

May 2020 Emerging therapeutic potential of mesenchymal stem cells in preeclampsia. Curr Hypertens Rep. https://link.springer.com/article/10.1007/s11906-020-1034-8

Apr 2020 Mechanisms of heart failure with preserved ejection fraction in the presence of diabetes mellitus. Translational Metabolic Disorder Research. https://doi.org/10.1016/j.tmsr.2020.04.002

Apr 2020 Diagnostics and prognostic potential of current biomarkers in heart failure with preserved ejection fraction: a systematic review and meta-analysis. https://www.medrxiv.org/content/10.1101/2020.04.18.20070482v1

March 2020 Overlapping Pathogenic Signalling Pathways and Biomarkers in Preeclampsia and Cardiovascular Disease. Pregnancy Hypertens. https://doi.org/10.1016/j.preghy.2020.03.011

March 2020 FKBPL, a novel player in cardiac ischaemia and fibrosis. Journal of Molecular and Cellular Cardiology. https://www.jmmc-online.com/article/S0022-2828(19)30233-0/abstract

Nov 2019  FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer. Br J Cancer

https://www.nature.com/articles/s41416-019-0649-5

 

Sep 2019 Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increased self-management and remote patient monitoring through mHealth solutions. BMC Health Serv Res.

ttps://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-019-4471-9 

Sep 2019 Association between Galectin-3 levels within central and peripheral venous blood, and adverse left ventricular remodelling after first acute myocardial infarction. Sci Rep

https://www.nature.com/articles/s41598-019-49511-4

 

Aug 2019 An Integrative Biomedical Informatics Approach to Elucidate the Similarities Between Pre-Eclampsia and Hypertension. Stud Health Technol Inform

file:///C:/Users/140037/Downloads/SHTI-264-SHTI190372%20(4).pdf.

July 2019 Association of Nrf2, SOD2 and GPX1 Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients. Toxins

https://www.mdpi.com/2072-6651/11/7/431.

June 2019 Markers of Oxidative Stress and Endothelial Dysfunction Predict Haemodialysis Patients Survival. Am J Nephrol.

https://www.karger.com/Article/Abstract/501300

Apr 2019 FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4. BMC Cancer

https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5500-0 

Apr 2019 Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair. FASEB J

https://www.fasebj.org/doi/10.1096/fj.201802056R?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub%3Dwww.ncbi.nlm.nih.gov& 

Dec 2018 Engaging hard-to-reach populations in research on health in pregnancy: the value of Boal's simultaneous dramaturgy. Arts Health. https://www.ncbi.nlm.nih.gov/pubmed/31038424 

Oct 2018 Downregulation of FKBPL influences metabolic and vascular function in experimental model of diabetes. Diabetologia. https://www.easd.org/virtualmeeting/home.html#!resources/downregulation-of-fkbpl-influences-metabolic-and-vascular-function-in-experimental-model-of-diabetes

June 2018 Mesenchymal stem cells influence trophoblast and endothelial cell functionality important for prevention of pre-eclampsia via a novel anti-angiogenic protein, FKBPL. Journal of Hypertension. https://journals.lww.com/jhypertension/Abstract/2018/06001/MESENCHYMAL_STEM_CELLS_INFLUENCE_TROPHOBLAST_AND.461.aspx

July 2018 FKBPL as a novel therapeutic target and prognostic biomarker in high grade serous ovarian cancer. Cancer Research. https://cancerres.aacrjournals.org/content/78/13_Supplement/LB-054.short

March 2018 4 The role of a novel anti-angiogenic protein, FKBPL, in angiogenesis associated with cardiac dysfunction. Heart. https://heart.bmj.com/content/104/Suppl_4/A2.1?utm_term=1-B&utm_content=americas&utm_campaign=alljjs&utm_medium=cpc&utm_source=trendmd

Feb 2018 Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis. Diabetic Medicine

https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.13523

Sept 2017 Elucidating the role of novel angiogenesis-related proteins, FKBPL and SIR-1, in trophoblast cells exposed to diabetic stimuli: potential implications for preeclampsia. Diabetologia.

https://www.easd.org/virtualmeeting/home.html#!resources/elucidating-the-role-of-novel-angiogenesis-related-proteins-fkbpl-and-sir-1-in-trophoblast-cells-exposed-to-diabetic-stimuli-potential-implications-for-preeclampsia-309100a7-346a-4def-aaf6-9244d56ef04e

Sept 2017 FKBPL, a novel angiogenesis-related protein, is downregulated in response to myocardial stress. Irish Journal of Medical Science. https://link.springer.com/article/10.1007/s11845-017-1670-4

 

Oct 2017 Elucidating the Pathogenesis of Pre-eclampsia Using In Vitro Models of Spiral Uterine Artery Remodelling. Curr Hypertens Rep. https://link.springer.com/article/10.1007%2Fs11906-017-0786-2  

Oct 2015 RALA-mediated delivery of FKBPL nucleic acid therapeutics. Nanomedicine (Lond).

https://www.futuremedicine.com/doi/abs/10.2217/nnm.15.115?rfr_dat=cr_pub%3Dpubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&journalCode=nnm 

March 2015 The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases. Curr Mol Pharmacol.

http://www.eurekaselect.com/131461/article 

Apr 2015 FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis. ATVB

https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.114.304539?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed 

Apr 2015 FKBPL: a marker of good prognosis in breast cancer. Oncotarget.

http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=3528&pubmed-linkout=1 

June 2014 Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen. Oncogene. https://www.nature.com/articles/onc2013306 

Jul 2013 Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway. Cli Cancer Res.

http://clincancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=23741069 

Feb 2013 The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway. PLoS ONE

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055075 

Women in STEM

© 2019 Dr. Lana McClements

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