top of page

- Claude Bernard -

“The joy of discovery is certainly the liveliest that the mind of man can ever feel”

April 2023 Quantitative Point of Care Tests for Timely Diagnosis of Early-Onset Preeclampsia with High Sensitivity and Specificity. Angewandte Chemie

March 2023 E-Cigarette Aerosol Condensate Leads to Impaired Coronary Endothelial Cell Health and Restricted Angiogenesis. International Journal of Molecular Sciences

March 2023 In vitro evaluation of a hybrid drug-delivery nanosystem for fibrosis prevention in cell therapy for Type 1 diabetes. Nanomedicine

Feb 2023 Diagnostic and prognostic biomarkers reflective of cardiac remodelling in diabetes mellitus: A scoping review. Diabetic Medicine

Feb 2023 FK506-Binding Protein like (FKBPL) Has an Important Role in Heart Failure with Preserved Ejection Fraction Pathogenesis with Potential Diagnostic Utility. Biomolecules

Jan 2023 A placenta-on-a-chip model to determine the regulation of FKBPL and galectin-3 in preeclampsia.

Cellular and Molecular Life Sciences

Dec 2022 Smart Drug-Delivery System of Upconversion Nanoparticles Coated with Mesoporous Silica for Controlled Release. Pharmaceutics

Dec 2022 New Treatment for Type 2 Diabetes Mellitus Using a Novel Bipyrazole Compound. Cells

Nov 2022 Challenges with Cell-based Therapies for Type 1 Diabetes Mellitus. Stem Cell Reviews and Reports.

Nov 2022 Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsia. Scientific Reports


Oct 2022 The emerging importance of immunophilins in fibrosis development. Molecular and Cellular Chemistry

Oct 2022 Systemic Biomarkers and Unique Pathways in Different Phenotypes of Heart Failure with Preserved Ejection Fraction. Biomolecules

Sept 2022 Loss of Expression of Antiangiogenic Protein FKBPL in Endometrioid Endometrial Carcinoma: Implications for Clinical Practice. Medicina

July 2022 Editorial: New Technologies for Women’s Health. Frontiers in Bioengineering and Biotechnology

June 2022 The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis. Biology of Sex Differences

Jan 2022 Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin–angiotensin-aldosterone system (RAAS) dysregulation. Chemico-Biological Interactions 

Jan 2022 Impact of reduced uterine perfusion pressure model of preeclampsia on metabolism of placenta, maternal and fetal hearts. Scientific Reports 

Aug 2021 Non-viral gene delivery utilizing RALA modulates sFlt-1 secretion, important for preeclampsia. Nanomedicine

July 2021 Plasma Amino Acids Metabolomics' Important in Glucose Management in Type 2 Diabetes. Frontiers in Pharmacology

June 2021 FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function. Frontiers in Endocrinology

June 2021 Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells. Biomedicine & Pharmacotherapy

April 2021 Considerations to Model Heart Disease in Women with Preeclampsia and Cardiovascular Disease. Cells 

April 2021 Characterisation of cardiac health in the reduced uterine perfusion pressure model and a 3D cardiac spheroid model, of preeclampsia. Biology of Sex Differences 

April 2021 3D Bioprinted cancer models: Revolutionizing personalized cancer therapy. Translational Oncology

March 2021 Extracellular Vesicles from Mesenchymal Stromal Cells for the Treatment of Inflammation-Related Conditions.International Journal of Molecular Sciences

March 2021 Simple-to-Operate Approach for Single Cell Analysis Using a Hydrophobic Surface and Nanosized Droplets.

Analytical Chemistry

Jan 2021 GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu. Oxidative medicine and cellular longevity

Dec 2020 FKBPL is associated with metabolic parameters and is a novel determinant of cardiovascular disease. Scientific Reports

Oct 2020 FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy. 

Aug 2020 Mechanisms of Key Innate Immune Cells in Early- and Late-Onset Preeclampsia. Frontiers in Immunology.

July 2020 Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment. Journal of Clinical Endocrinology and Metabolism.

July 2020 Cardiac Health in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia. Journal of Paediatrics and Child Health.

June 2020 Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives. Cells.


May 2020 Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections. Front. Bioeng. Biotechnol. 

May 2020 Emerging therapeutic potential of mesenchymal stem cells in preeclampsia. Curr Hypertens Rep.

Apr 2020 Mechanisms of heart failure with preserved ejection fraction in the presence of diabetes mellitus. Translational Metabolic Disorder Research.


Apr 2020 Diagnostics and prognostic potential of current biomarkers in heart failure with preserved ejection fraction: a systematic review and meta-analysis.

March 2020 Overlapping Pathogenic Signalling Pathways and Biomarkers in Preeclampsia and Cardiovascular Disease. Pregnancy Hypertens.

March 2020 FKBPL, a novel player in cardiac ischaemia and fibrosis. Journal of Molecular and Cellular Cardiology.

Nov 2019  FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer. Br J Cancer

Sep 2019 Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increased self-management and remote patient monitoring through mHealth solutions. BMC Health Serv Res.


Sep 2019 Association between Galectin-3 levels within central and peripheral venous blood, and adverse left ventricular remodelling after first acute myocardial infarction. Sci Rep


Aug 2019 An Integrative Biomedical Informatics Approach to Elucidate the Similarities Between Pre-Eclampsia and Hypertension. Stud Health Technol Inform


July 2019 Association of Nrf2, SOD2 and GPX1 Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients. Toxins

June 2019 Markers of Oxidative Stress and Endothelial Dysfunction Predict Haemodialysis Patients Survival. Am J Nephrol.

Apr 2019 FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4. BMC Cancer 

Apr 2019 Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair. FASEB J 

Dec 2018 Engaging hard-to-reach populations in research on health in pregnancy: the value of Boal's simultaneous dramaturgy. Arts Health. 

Oct 2018 Downregulation of FKBPL influences metabolic and vascular function in experimental model of diabetes. Diabetologia.!resources/downregulation-of-fkbpl-influences-metabolic-and-vascular-function-in-experimental-model-of-diabetes

June 2018 Mesenchymal stem cells influence trophoblast and endothelial cell functionality important for prevention of pre-eclampsia via a novel anti-angiogenic protein, FKBPL. Journal of Hypertension.

July 2018 FKBPL as a novel therapeutic target and prognostic biomarker in high grade serous ovarian cancer. Cancer Research.

March 2018 4 The role of a novel anti-angiogenic protein, FKBPL, in angiogenesis associated with cardiac dysfunction. Heart.

Feb 2018 Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis. Diabetic Medicine

Sept 2017 Elucidating the role of novel angiogenesis-related proteins, FKBPL and SIR-1, in trophoblast cells exposed to diabetic stimuli: potential implications for preeclampsia. Diabetologia.!resources/elucidating-the-role-of-novel-angiogenesis-related-proteins-fkbpl-and-sir-1-in-trophoblast-cells-exposed-to-diabetic-stimuli-potential-implications-for-preeclampsia-309100a7-346a-4def-aaf6-9244d56ef04e

Sept 2017 FKBPL, a novel angiogenesis-related protein, is downregulated in response to myocardial stress. Irish Journal of Medical Science.


Oct 2017 Elucidating the Pathogenesis of Pre-eclampsia Using In Vitro Models of Spiral Uterine Artery Remodelling. Curr Hypertens Rep.  

Oct 2015 RALA-mediated delivery of FKBPL nucleic acid therapeutics. Nanomedicine (Lond). 

March 2015 The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases. Curr Mol Pharmacol. 

Apr 2015 FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis. ATVB 

Apr 2015 FKBPL: a marker of good prognosis in breast cancer. Oncotarget.[]=3528&pubmed-linkout=1 

June 2014 Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen. Oncogene. 

Jul 2013 Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway. Cli Cancer Res. 

Feb 2013 The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway. PLoS ONE 

bottom of page