- Claude Bernard -
“The joy of discovery is certainly the liveliest that the mind of man can ever feel”
April 2023 Quantitative Point of Care Tests for Timely Diagnosis of Early-Onset Preeclampsia with High Sensitivity and Specificity. Angewandte Chemie
https://onlinelibrary.wiley.com/doi/full/10.1002/ange.202301193
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March 2023 E-Cigarette Aerosol Condensate Leads to Impaired Coronary Endothelial Cell Health and Restricted Angiogenesis. International Journal of Molecular Sciences
https://www.mdpi.com/1422-0067/24/7/6378
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https://www.futuremedicine.com/doi/abs/10.2217/nnm-2022-0231
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Feb 2023 Diagnostic and prognostic biomarkers reflective of cardiac remodelling in diabetes mellitus: A scoping review. Diabetic Medicine
https://onlinelibrary.wiley.com/doi/full/10.1111/dme.15064
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Feb 2023 FK506-Binding Protein like (FKBPL) Has an Important Role in Heart Failure with Preserved Ejection Fraction Pathogenesis with Potential Diagnostic Utility. Biomolecules
https://www.mdpi.com/2218-273X/13/2/395
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Jan 2023 A placenta-on-a-chip model to determine the regulation of FKBPL and galectin-3 in preeclampsia.
Cellular and Molecular Life Sciences
https://link.springer.com/article/10.1007/s00018-022-04648-w
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Dec 2022 Smart Drug-Delivery System of Upconversion Nanoparticles Coated with Mesoporous Silica for Controlled Release. Pharmaceutics
https://www.mdpi.com/1999-4923/15/1/89
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Dec 2022 New Treatment for Type 2 Diabetes Mellitus Using a Novel Bipyrazole Compound. Cells
https://www.mdpi.com/2073-4409/12/2/267
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Nov 2022 Challenges with Cell-based Therapies for Type 1 Diabetes Mellitus. Stem Cell Reviews and Reports.
https://link.springer.com/article/10.1007/s12015-022-10482-1
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Nov 2022 Maternal plasma proteome profiling of biomarkers and pathogenic mechanisms of early-onset and late-onset preeclampsia. Scientific Reports
https://www.nature.com/articles/s41598-022-20658-x
Oct 2022 The emerging importance of immunophilins in fibrosis development. Molecular and Cellular Chemistry
https://link.springer.com/article/10.1007/s11010-022-04591-1
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Oct 2022 Systemic Biomarkers and Unique Pathways in Different Phenotypes of Heart Failure with Preserved Ejection Fraction. Biomolecules
https://www.mdpi.com/2218-273X/12/10/1419
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Sept 2022 Loss of Expression of Antiangiogenic Protein FKBPL in Endometrioid Endometrial Carcinoma: Implications for Clinical Practice. Medicina
https://www.mdpi.com/1648-9144/58/10/1330
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July 2022 Editorial: New Technologies for Women’s Health. Frontiers in Bioengineering and Biotechnology
https://www.frontiersin.org/articles/10.3389/fbioe.2022.969389/full
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June 2022 The diagnostic potential of oxidative stress biomarkers for preeclampsia: systematic review and meta-analysis. Biology of Sex Differences
https://bsd.biomedcentral.com/articles/10.1186/s13293-022-00436-0
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https://www.sciencedirect.com/science/article/pii/S0009279721003768
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Jan 2022 Impact of reduced uterine perfusion pressure model of preeclampsia on metabolism of placenta, maternal and fetal hearts. Scientific Reports
https://www.nature.com/articles/s41598-022-05120-2
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https://www.futuremedicine.com/doi/abs/10.2217/nnm-2021-0180
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July 2021 Plasma Amino Acids Metabolomics' Important in Glucose Management in Type 2 Diabetes. Frontiers in Pharmacology https://doi.org/10.3389/fphar.2021.695418
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June 2021 FKBPL and SIRT-1 Are Downregulated by Diabetes in Pregnancy Impacting on Angiogenesis and Endothelial Function. Frontiers in Endocrinology
https://doi.org/10.3389/fendo.2021.650328
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June 2021 Stem cell-based approaches in cardiac tissue engineering: controlling the microenvironment for autologous cells. Biomedicine & Pharmacotherapy
https://doi.org/10.1016/j.biopha.2021.111425
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April 2021 Considerations to Model Heart Disease in Women with Preeclampsia and Cardiovascular Disease. Cells
https://europepmc.org/article/pmc/pmc8070848
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April 2021 Characterisation of cardiac health in the reduced uterine perfusion pressure model and a 3D cardiac spheroid model, of preeclampsia. Biology of Sex Differences
https://bsd.biomedcentral.com/articles/10.1186/s13293-021-00376-1
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April 2021 3D Bioprinted cancer models: Revolutionizing personalized cancer therapy. Translational Oncology https://doi.org/10.1016/j.tranon.2021.101015
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March 2021 Extracellular Vesicles from Mesenchymal Stromal Cells for the Treatment of Inflammation-Related Conditions.International Journal of Molecular Sciences
https://doi.org/10.3390/ijms22063023
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March 2021 Simple-to-Operate Approach for Single Cell Analysis Using a Hydrophobic Surface and Nanosized Droplets.
Analytical Chemistry
https://doi.org/10.1021/acs.analchem.0c05026
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Jan 2021 GSTM1 Modulates Expression of Endothelial Adhesion Molecules in Uremic Milieu. Oxidative medicine and cellular longevity https://doi.org/10.1155/2021/6678924
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Dec 2020 FKBPL is associated with metabolic parameters and is a novel determinant of cardiovascular disease. Scientific Reports
https://doi.org/10.1038/s41598-020-78676-6
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Oct 2020 FKBPL and SIRT-1, key angiogenesis proteins, are downregulated by diabetes in pregnancy. https://www.medrxiv.org/content/10.1101/2020.10.06.20208116v1
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Aug 2020 Mechanisms of Key Innate Immune Cells in Early- and Late-Onset Preeclampsia. Frontiers in Immunology.
https://www.frontiersin.org/articles/10.3389/fimmu.2020.01864/full
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July 2020 Role of a novel angiogenesis FKBPL-CD44 pathway in preeclampsia risk stratification and mesenchymal stem cell treatment. Journal of Clinical Endocrinology and Metabolism. https://doi.org/10.1210/clinem/dgaa403
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July 2020 Cardiac Health in the Reduced Uterine Perfusion Pressure Rat Model of Preeclampsia. Journal of Paediatrics and Child Health. https://onlinelibrary.wiley.com/doi/10.1111/jpc.14868
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June 2020 Top Notch Targeting Strategies in Cancer: A Detailed Overview of Recent Insights and Current Perspectives. Cells. https://www.mdpi.com/2073-4409/9/6/1503
May 2020 Can Stem Cells Beat COVID-19: Advancing Stem Cells and Extracellular Vesicles Toward Mainstream Medicine for Lung Injuries Associated With SARS-CoV-2 Infections. Front. Bioeng. Biotechnol. https://doi.org/10.3389/fbioe.2020.00554
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May 2020 Emerging therapeutic potential of mesenchymal stem cells in preeclampsia. Curr Hypertens Rep. https://link.springer.com/article/10.1007/s11906-020-1034-8
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Apr 2020 Mechanisms of heart failure with preserved ejection fraction in the presence of diabetes mellitus. Translational Metabolic Disorder Research. https://doi.org/10.1016/j.tmsr.2020.04.002
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Apr 2020 Diagnostics and prognostic potential of current biomarkers in heart failure with preserved ejection fraction: a systematic review and meta-analysis. https://www.medrxiv.org/content/10.1101/2020.04.18.20070482v1
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March 2020 Overlapping Pathogenic Signalling Pathways and Biomarkers in Preeclampsia and Cardiovascular Disease. Pregnancy Hypertens. https://doi.org/10.1016/j.preghy.2020.03.011
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March 2020 FKBPL, a novel player in cardiac ischaemia and fibrosis. Journal of Molecular and Cellular Cardiology. https://www.jmmc-online.com/article/S0022-2828(19)30233-0/abstract
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Nov 2019 FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer. Br J Cancer
https://www.nature.com/articles/s41416-019-0649-5
Sep 2019 Service evaluation of diabetes management during pregnancy in a regional maternity hospital: potential scope for increased self-management and remote patient monitoring through mHealth solutions. BMC Health Serv Res.
ttps://bmchealthservres.biomedcentral.com/articles/10.1186/s12913-019-4471-9
Sep 2019 Association between Galectin-3 levels within central and peripheral venous blood, and adverse left ventricular remodelling after first acute myocardial infarction. Sci Rep
https://www.nature.com/articles/s41598-019-49511-4
Aug 2019 An Integrative Biomedical Informatics Approach to Elucidate the Similarities Between Pre-Eclampsia and Hypertension. Stud Health Technol Inform
file:///C:/Users/140037/Downloads/SHTI-264-SHTI190372%20(4).pdf.
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July 2019 Association of Nrf2, SOD2 and GPX1 Polymorphisms with Biomarkers of Oxidative Distress and Survival in End-Stage Renal Disease Patients. Toxins
https://www.mdpi.com/2072-6651/11/7/431.
June 2019 Markers of Oxidative Stress and Endothelial Dysfunction Predict Haemodialysis Patients Survival. Am J Nephrol.
https://www.karger.com/Article/Abstract/501300
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Apr 2019 FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4. BMC Cancer
https://bmccancer.biomedcentral.com/articles/10.1186/s12885-019-5500-0
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Apr 2019 Hypercapnic acidosis induces mitochondrial dysfunction and impairs the ability of mesenchymal stem cells to promote distal lung epithelial repair. FASEB J
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Dec 2018 Engaging hard-to-reach populations in research on health in pregnancy: the value of Boal's simultaneous dramaturgy. Arts Health. https://www.ncbi.nlm.nih.gov/pubmed/31038424
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Oct 2018 Downregulation of FKBPL influences metabolic and vascular function in experimental model of diabetes. Diabetologia. https://www.easd.org/virtualmeeting/home.html#!resources/downregulation-of-fkbpl-influences-metabolic-and-vascular-function-in-experimental-model-of-diabetes
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June 2018 Mesenchymal stem cells influence trophoblast and endothelial cell functionality important for prevention of pre-eclampsia via a novel anti-angiogenic protein, FKBPL. Journal of Hypertension. https://journals.lww.com/jhypertension/Abstract/2018/06001/MESENCHYMAL_STEM_CELLS_INFLUENCE_TROPHOBLAST_AND.461.aspx
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July 2018 FKBPL as a novel therapeutic target and prognostic biomarker in high grade serous ovarian cancer. Cancer Research. https://cancerres.aacrjournals.org/content/78/13_Supplement/LB-054.short
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March 2018 4 The role of a novel anti-angiogenic protein, FKBPL, in angiogenesis associated with cardiac dysfunction. Heart. https://heart.bmj.com/content/104/Suppl_4/A2.1?utm_term=1-B&utm_content=americas&utm_campaign=alljjs&utm_medium=cpc&utm_source=trendmd
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Feb 2018 Risk of pre-eclampsia in women taking metformin: a systematic review and meta-analysis. Diabetic Medicine
https://onlinelibrary.wiley.com/doi/abs/10.1111/dme.13523
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Sept 2017 Elucidating the role of novel angiogenesis-related proteins, FKBPL and SIR-1, in trophoblast cells exposed to diabetic stimuli: potential implications for preeclampsia. Diabetologia.
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Sept 2017 FKBPL, a novel angiogenesis-related protein, is downregulated in response to myocardial stress. Irish Journal of Medical Science. https://link.springer.com/article/10.1007/s11845-017-1670-4
Oct 2017 Elucidating the Pathogenesis of Pre-eclampsia Using In Vitro Models of Spiral Uterine Artery Remodelling. Curr Hypertens Rep. https://link.springer.com/article/10.1007%2Fs11906-017-0786-2 ​
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Oct 2015 RALA-mediated delivery of FKBPL nucleic acid therapeutics. Nanomedicine (Lond).
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March 2015 The Role of Peptidyl Prolyl Isomerases in Aging and Vascular Diseases. Curr Mol Pharmacol.
http://www.eurekaselect.com/131461/article
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Apr 2015 FKBPL is a critical antiangiogenic regulator of developmental and pathological angiogenesis. ATVB
https://www.ahajournals.org/doi/full/10.1161/ATVBAHA.114.304539?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
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Apr 2015 FKBPL: a marker of good prognosis in breast cancer. Oncotarget.
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June 2014 Identification of RBCK1 as a novel regulator of FKBPL: implications for tumor growth and response to tamoxifen. Oncogene. https://www.nature.com/articles/onc2013306
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Jul 2013 Targeting treatment-resistant breast cancer stem cells with FKBPL and its peptide derivative, AD-01, via the CD44 pathway. Cli Cancer Res.
http://clincancerres.aacrjournals.org/cgi/pmidlookup?view=long&pmid=23741069
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Feb 2013 The anti-migratory effects of FKBPL and its peptide derivative, AD-01: regulation of CD44 and the cytoskeletal pathway. PLoS ONE
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0055075
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